Treatment Recommendations

Compare AI-suggested treatment plans for Grace Karimu

Medications Lifestyle Procedures Follow-up

Parameter	Amlodipine 5mg once daily	Lisinopril 10mg once daily	Hydrochlorothiazide 25mg once daily
Drug Class	CCB	ACE Inhibitor	Thiazide Diuretic
Efficacy Score	88%	82%	74%
Side Effects	Peripheral edema, flushing, dizziness	Dry cough, hyperkalemia, dizziness	Hypokalemia, hyperuricemia, photosensitivity
Contraindications	Severe aortic stenosis, cardiogenic shock	Bilateral renal artery stenosis, pregnancy, angioedema	Anuria, severe renal impairment, sulfonamide allergy
Dosage	5mg PO once daily, may increase to 10mg	10mg PO once daily, may titrate to 40mg	25mg PO once daily, max 50mg

Clinical Evidence Level A

Based on JNC-8 guidelines and SPRINT trial data. Amlodipine demonstrated superior systolic BP reduction in the ALLHAT trial for patients with metabolic syndrome.

Source: ALLHAT, SPRINT, JNC-8 Guidelines

Drug Interactions Safe

Metformin 500mg interaction check completed. No significant drug-drug interactions identified with any of the three proposed antihypertensive agents.

Checked against current medication: Metformin 500mg

Outcome Prediction Moderate

AI model predicts 78% probability of achieving target BP (<130/80 mmHg) within 8 weeks with Amlodipine monotherapy. Combination therapy may be required.

Confidence: 78% | Model: ClinicalBERT v3.2